CALRETICULIN-MUTANT PROTEINS INDUCE MEGAKARYOCYTIC SIGNALING TO TRANSFORM HEMATOPOIETIC CELLS AND UNDERGO ACCELERATED DEGRADATION AND GOLGI-MEDIATED SECRETION

Calreticulin-mutant proteins induce megakaryocytic signaling to transform hematopoietic cells and undergo accelerated degradation and Golgi-mediated secretion

Wheelchair Accessories Abstract Background Somatic calreticulin (CALR), Janus kinase 2 (JAK2), and thrombopoietin receptor (MPL) mutations essentially show mutual exclusion in myeloproliferative neoplasms (MPN), suggesting that they activate common oncogenic pathways.Recent data have shown that MPL function is essential for CALR mutant-driven MPN.H

read more

Application of Kinoform CGHs to an ID Tag System

In this Butter Dish paper, we successfully apply multilevel kinoform computer-generated hologram (CGH) patterns, which are recorded on a fine texture paper by a photo printer, into the hologram identification (ID) tag system.The 11-level kinoform CGH images are generated on our tag samples by a modified simulated annealing method at a low quantizat

read more